?????? ?? ???, ????? ???? ?? ??? ?? ?????? ???? ??? ?????? ?? ??????????? ?? ???? ???? ????? ?? ???? ?? ???? ?? ???? ?? ??? ???? ???????????????? ???? ?? ??? ????? ???? ??????????Promethazine is metabolized with the liver to many different compounds; the sulfoxides of promethazine and N-demethylpromethazine are classified as the predominant metabol